Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea | House in Panacea

9.6 (22 Reviews) |   4 Bedrooms  2 Bathrooms  8 Guests
Panacea House | Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea

4 Bedroom House in Panacea

Welcome to your waterfront cottage on beautiful Ochlockonee Bay, where life slows down and the rhythms of Florida’s Forgotten Coast take over. Here, the days are measured by the tides, the calls of ospreys overhead, and spectacular sunsets that paint the water each evening. Fun fact: the name Ochlockonee comes from the Apalachee and Creek peoples who lived near the river and is commonly translated as “yellow water,” a nod to the river’s naturally tea-colored, tannin-rich waters.
Wake up with a cup of complimentary coffee in the glassed-in sunroom, spend the day exploring the shoreline, then relax on the back deck as pelicans glide by and the evening sky comes alive with color. Just outside the back door is your own private bay beach, where you can stroll along the water’s edge, search for shells, watch fiddler crabs at work, and enjoy the peaceful beauty of the Ochlockonee River. The surrounding salt marsh and bay form one of nature’s great nurseries, supporting countless fish, crabs, birds, and other wildlife. These waters are perfect for watching wildlife, fishing, paddling, or simply taking in the ever-changing tides.
Mashes Sands Beach is just about a mile away and offers a sandy swimming beach, boat ramp, and some of the most beautiful sunrises on Florida’s Gulf Coast. You’re only minutes from Panacea and not too far from other charming fishing villages like St. Marks, Lanark, and Carrabelle. Our local communities have depended on these waters for generations. Fresh local seafood is a highlight here, think just-caught grouper, sweet Gulf shrimp, blue crab, and Apalachicola oysters, often served the same day they’re harvested. Our commercial fishing heritage continues to evolve, and you’ll now find thriving oyster aquaculture farms dotting the nearby waters, producing some of the freshest oysters in the region.
For those who enjoy exploring on two wheels, the Capital City to Sea Bike Trail is easily accessible from the cottage. Starting here on the coast, you can follow the trail inland through some of the most beautiful scenery in North Florida. A favorite stretch follows Coastal Hwy, where expansive salt marshes stretch to the horizon, ospreys soar overhead, and wading birds feed along the tidal creeks. Or head toward Sopchoppy using Surf Road where you’ll pass quiet ponds filled with blooming water lilies, native wildflowers, towering longleaf pines, shady forests, and peaceful stretches of Old Florida that few visitors ever experience. The changing landscapes make every mile feel different, offering countless opportunities to stop for photographs, birdwatching, or simply soaking in the scenery.
You may even spot one of our area’s famous white squirrels during your stay. These unique little residents have become a beloved local treasure and are always a delightful surprise for visitors.
Two kayaks are available for guest enjoyment and are intended to be launched directly from the property. They may not be transported to other launch locations. Life jackets are provided and must be worn at all times while using the kayaks. Guests use the kayaks at their own risk and assume all responsibility for their safety while on the water. As you paddle, you’re tracing routes that have been used for centuries: first by Indigenous peoples navigating these waterways, and later by generations of fishermen who relied on the bay for their livelihood. Today, the calm waters remain ideal for exploring hidden inlets, observing wildlife up close, and experiencing the quiet beauty of the coast.
Please note that the dock is permanently closed, is not functional, and is not available for guest use. The waterfront, private bay beach, and panoramic views remain the true highlights of the property.
As with any natural body of water, conditions can change due to weather, tides, and seasonal environmental factors. We encourage guests to check current water advisories before swimming or wading at area beaches or in the bay and to use their own judgment when enjoying the water.
One of the joys of Old Florida is experiencing nature much as it has existed for generations. Depending on the season, mosquitoes and no-see-ums may be present, particularly around sunrise and sunset, so we recommend bringing insect repellent if you plan to spend time outdoors. Native wildlife, including dolphins, shorebirds, sea turtles, deer, alligators, foxes, and occasionally black bears, also call this area home. Keep an eye on the water during cooler months, you may even be lucky enough to spot a manatee. We ask guests to be mindful of their surroundings, keep food secured, and enjoy wildlife from a respectful distance.
Whether you spend your days paddling the quiet bay, exploring nearby beaches, watching the sunset from the deck, or simply listening to the breeze through the pines, we hope you’ll leave feeling refreshed, restored, and a little more connected to the timeless beauty of Florida’s Forgotten Coast.
Upcoming Local Events
Summer Farmers Market
Panacea Community Garden - August 1st
The Gathering / Community Dinner
White Squirrel Nursery - July 25th @ 6p

Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea is located in Panacea. Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea provides accommodation, featuring Bedding/Linens, Kitchen, Air Conditioner, among other amenities. This House features Air Conditioner, Parking and TV to make your stay a comfortable one.

Sunsets & Serenity: Tranquil Waterfront Escape on the Ochlockonee in Panacea has 4 Bedrooms , 2 Bathrooms, and max occupancy of 8 people. The minimum rental for this property is 1 nights, but this can change depending on the season you plan on staying. Previous guests have given good rated it, and VRBO labeled it a top-rated House because of the excellent services rendered by the owner or manager of this House, and has consistently provided great experiences for their guests. Most families or guests that use it recommend it to their friends and some of them are repeat guests. House has a friendly neighborhood, and the Panacea has interesting places to visit. If you want to learn more about the House in Panacea, such as places to visit and things to do nearby, you can check below to learn more.

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Amenities

Air Conditioner
Parking
TV
View
Ocean View
Balcony/Terrace
Oceanfront
Security/Safety
Sports/Activities
Bedding/Linens
Wellness Facilities
Fireplace/Heating
Entertainment
Barbecue/Outdoor Cooking
Child Friendly
Internet
Kitchen
Laundry

Facility Overview

Air Conditioner
  • Air conditioning
  • Heating
Bathrooms
  • Shampoo
  • Shower
  • Soap
  • Toilet paper
  • Hair dryer
  • 2 bathrooms
  • Towels provided
Bedroom
  • 4 bedrooms
  • Bed sheets provided
  • Dining table
  • Dining room
  • Fireplace
Kitchen
  • Toaster
  • Refrigerator
  • Ice maker
  • Oven
  • Dishwasher
  • Spices
  • Stovetop
  • Microwave
  • Paper towels
Laundry
  • Laundry facilities
  • Washing machine and dryer
Ocean view
  • Near the beach
  • Beach towels
Parking
  • Onsite parking
Pet Friendly
  • No pets allowed
Accessibility
  • Smoke-free property
  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • No elevator (single level property)
Activities
  • Cycling nearby
  • Swimming nearby
  • Kayaking nearby
  • Power boating nearby
  • Golf nearby
  • Hiking/biking trails nearby
  • Hiking nearby
  • Kayak on site
  • Wildlife and game walks nearby
  • Ecotours nearby
Entertainment
  • DVD player
  • Smart TV with cable/satellite service
General
  • Unit size: 1988 sq ft (185 sq m)
  • English
  • On the waterfront
  • Near the bay
  • On the river
  • Near the sea
  • In a rural location
Guest Services
  • Children's toys
  • Iron/ironing board
Internet
  • Free WiFi
Outdoors
  • Barbecue grill
  • Patio
  • Garden
  • Outdoor furniture
Security/Safety
  • First aid kit
  • Fire extinguisher
  • No carbon monoxide detector (host has indicated there is no carbon monoxide detector on the property but there are gas appliances; consider bringing a portable detector with you on the trip)
  • Smoke detector installed (host has indicated there is a smoke detector on the property)
  • Deadbolt lock

Policies

Check-in
Check-in time starts at 4:00 pm contactless check-in available minimum check-in age: 30
Check-out
Check-out before 10:00 am contactless check-out available
Child Policy
Children are welcome.
Event Policy
No events allowed
Pet Policy
Pets not allowed
Smoking Policy
Smoking is not permitted

Extra-person charges may apply and vary depending on property policy government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges host has indicated there is a smoke detector on the property host has indicated there is no carbon monoxide detector on the property but there are gas appliances; consider bringing a portable detector with you on the trip onsite parties or group events are strictly prohibited safety features at this property include a fire extinguisher, a first aid kit, and a deadbolt lock special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed this property has outdoor spaces, such as balconies, patios, terraces which may not be suitable for children; if you have concerns, we recommend contacting the property prior to your arrival to confirm they can accommodate you in a suitable room this property is managed through our partner, vrbo. you will receive an email from vrbo with a link to a vrbo account, where you can change or cancel your reservation

Reviews

Andy D.
Nov 30, 2025 03:34:28 AM
Review Score:   6
Summary: A little disappointed that the dock was not usable. Both mattresses on the twin beds were very uncomfortable, the same with the couch and loveseat - all handles for the reclining seats were broken off and their seats are not very comfortable, I assume just worn down over many years. Queen/king beds were great, and very good internet. This would be a great rental house if the furniture was updated.
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FAQ's

Is this property pet-friendly for guests?

No, pets are not allowed at this property. Check the guest reviews to learn what guests had to share.

Does the property have a swimming pool?

No, this Panacea house does not have a swimming pool. Check the Facility Overview section for details about the pool and other available facilities.

How much does it cost per night to stay in property?

Best-rates for the Panacea house starts from $387 per night with includes Air Conditioner, TV, Balcony/Terrace, Wellness Facilities, Internet, Parking, View, Ocean View, Oceanfront, Security/Safety, Child Friendly, Laundry, Sports/Activities, Fireplace/Heating, Entertainment, Barbecue/Outdoor Cooking, Bedding/Linens, Kitchen with all other facilities. matches every traveler with their perfect accommodation, whether you are traveling with a group, friends, family, or pets.

Is property a family-friendly place to stay?

Based on the information we have received from the owner or our partner, this is considered to be a family-friendly property. Families have rated this house Good or guests have recommended them suitable for families. As reported by the owner or manager, the house has specified that children are welcome. Please see details about suitability for your family or inquire with the property to learn more.

Is the property wheelchair accessible or offer services for disabled guests?

Based on the information received from our partner, the Panacea house has not specified they are wheelchair accessible. Likewise, there is not an elevator specified as being available at the property. Specific accessibility details may be addressed in the property details section of this page.

What is the minimum night stay policy for the property?

Based on the information reported by the owner or manager, the Panacea house indicates 1 day stay policy at this house. Guests are cautioned that the minimum stay policy may differ based on seasonality or availability and may be at the discretion of the owner or manager.

What cancellation policy is in place for property?

Guests are cautioned that the cancellation policy may differ based on seasonality, availability, or current travel restrictions. Guests should also be aware that this policy may be subject to change and should be confirmed prior to booking. More details may be available on this page in the property description. However, early check-in or late check-out can sometimes be negotiated between the guest and the owner or the manager of this property.

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